Safety and Performance Aspects, Development, Qualification of High Burnup, HBU, Nuclear Fuels, Water Cooled Reactors, WCRs, Fuel Burnup, Nuclear Engineering, Safety Measures, Safety and Technological Challenges, Licensing, Design of the Reactor Core, Nuclear Power Plants, Industry Trends, Technical and Scientific Support Organizations, TSOs, Regulatory Organizations, Operators, Nuclear Utilities, Feasibility Studies, Operational Limits, Member States, State of Art, Physical Phenomena, Multiphysics and Multiscale Modelling, Simulation Capabilities, Experimental Testing, In-Pile, Out of Pile, Numerical Models, Design Basis Accident, DBA, Loss of Coolant Accident, LOCA, Reactivity Insertion Accident, RIA, Lead Test Assembly, LTA, Lead Test Rod, LTR, Thermomechanical Codes, Validation, Advanced Fuel, Cladding Designs, Irradiation of Test Fuel Rods, Pool-Site Inspections, Post-Irradiation Examination, PIE, Design Codes, Methods for HBU Rates, Safety Reviews, Future Activities, Phenomenological Knowledge and Insights, TRANSURANUS Code Application, Fuel Fragmentation Dispersal, SCIANTIX Grain-Scale Code, Future International Cooperation, Review